By Robert Preidt
FRIDAY, Dec. 18, 2020 (HealthDay Information) — COVID-19 is much extra dangerous and lethal than the seasonal flu, new research verify.
Researchers analyzed U.S. Division of Veterans Affairs knowledge on greater than 3,600 sufferers hospitalized with COVID-19 between Feb. 1 and June 17 of this 12 months, and greater than 12,600 hospitalized with the flu between Jan. 1, 2017 and Dec. 31, 2019. The typical age of sufferers in each teams was 69.
The loss of life fee amongst COVID-19 sufferers was 18.5%, whereas it was 5.3% for these with the flu. These with COVID had been practically 5 instances extra more likely to die than flu sufferers, in keeping with the research revealed on-line Dec. 15 within the BMJ.
COVID-19 sufferers with the best danger of loss of life included these aged 75 and older who additionally had persistent kidney illness or dementia, and Blacks who had been overweight, or who had diabetes or kidney illness.
The research additionally discovered that COVID-19 sufferers had been 4 instances extra more likely to require respiration machines, practically 2.5 instances extra more likely to be admitted to intensive care, and stayed within the hospital a mean of three days longer than flu sufferers.
A separate research from France, revealed on-line Dec. 17 in The Lancet Respiratory Medication journal, arrived at comparable conclusions: Practically twice as many individuals had been admitted to the hospital for COVID-19 on the peak of the pandemic than had been for influenza on the peak of the 2018/2019 flu season. And the loss of life fee was virtually thrice greater.
The French crew, led by Dr. Pascale Tubert-Bitter, analysis director at L’Institut Nationwide de la Santé et de la Recherche Médicale (Inserm), and Catherine Quantin, from the College Hospital of Dijon and Inserm, in contrast knowledge from COVID-19 sufferers admitted to the hospital over a two-month interval in spring 2020 with influenza sufferers admitted over a three-month interval throughout the seasonal flu outbreak of 2018/2019.
“The discovering that the COVID-19 loss of life fee was thrice greater than for seasonal influenza is especially placing when reminded that the 2018/2019 flu season had been the worst previously 5 years in France when it comes to variety of deaths,” Quantin famous in a Lancet information launch.
Tubert-Bitter added, “Taken collectively, our findings clearly point out that COVID-19 is rather more severe than seasonal influenza. At a time when no therapy has been proven to be efficient at stopping extreme illness in COVID-19 sufferers, this research highlights the significance of all measures of bodily prevention and underlines the significance of efficient vaccines.”
U.S. researchers stated an enormous shock of their research was that COVID-19 sufferers had the next danger of growing diabetes, with 9 extra circumstances per 100 than flu sufferers.
“These sufferers did not have diabetes till they acquired COVID-19,” stated research senior writer Dr. Ziyad Al-Aly, an assistant professor of medication at Washington College in St. Louis. “Then their blood sugar spiked, they usually wanted big doses of insulin. Is the diabetes reversible, or will it require long-term administration? Will or not it’s kind 1 or kind 2 diabetes? We simply do not know as a result of COVID-19 barely existed a 12 months in the past.”
One other discovering was that COVID-19 sufferers had the next danger of acute kidney harm and extreme sepsis shock. For each problems, there have been a mean of 6extra circumstances per 100 COVID-19 sufferers than amongst flu sufferers.
Additionally, COVID-19 sufferers had been extra more likely to want medicines to deal with severely low blood strain, a situation that may result in organ harm and loss of life. The speed was 11.5 extra circumstances per 100 sufferers than amongst flu sufferers.
“Many high-profile, public comparisons between COVID-19 and the flu have been made; nonetheless, these comparisons principally had been drawn utilizing disparate knowledge and statistical strategies which have resulted in a variety of conjecture. Our analysis represents an apples-to-apples comparability between the 2 ailments,” Al-Aly stated in a college information launch.
“A deeper understanding of the well being dangers of COVID-19 helps to anticipate demand for well being care companies and to undertaking mortality with higher accuracy,” he added.
“We all know so little about COVID-19 due to its newness,” Al-Aly famous. “I am undecided why Black sufferers endure and die extra. My hunch is that the trigger pertains to racial disparities in well being care, however there could possibly be different components that we do not but know.”
The U.S. Facilities for Illness Management and Prevention has extra on COVID-19.
SOURCES: Washington College in St. Louis, information launch, Dec. 15, 2020; The Lancet Respiratory Medication, information launch, Dec. 17, 2020